415 million people suffer from a disease _ diabetes in the world, any one of all 11 of the adult population in the world living with diabetes and that 46% of people with undiagnosed diabetes. It showed the vaccine (Bacillus Calmette-Guerin), which was used for more than 100 years to treat tuberculosis, promising results in the treatment of diabetes. BCG vaccine is currently also used W securely to cure cancer _ bladder.
Was advertised during the 75th session of the American Diabetes Association to FDA FDA BCG vaccine test will take place on 150 people in an advanced stage of type 1 diabetes.
The body of a person with type 1 diabetes do not produce insulin because the device _ immune system destroys the cells which create insulin. T cells are produced, and these cells create problems in the pancreas, where insulin is produced. And it turns out that the vaccine BCG works to eliminate these T cells.
When injecting diabetic, noted an increase in levels of a substance called tumor necrosis factor TNF “high level resulted in the destruction of T cells pancreas, hindering the production of insulin, so” HealthSouth site auernis “(The Health Awareness).
In a previous experiment, patients were injected with tuberculosis vaccine twice within a time frame for 4 weeks. The results showed the disappearance of T cells, and that some of the mothers had been already begun in insulin secretion.
He Dr Denis vaustman, Director of the Massachusetts General Hospital Laboratory of Immunology in Boston, great enthusiasm for the results shown by the BCG vaccine, saying: “in the first stage of the experiment () been proven statistically significant response to BCG, but our goal in (this experience) creating durable therapeutic response. And it will work again for further testing on people with type I diabetes for many years. This is not a test, but a deliberate effort to create a system that would address the disease even in advanced stages.
The same formula
And due to start a new round of experiments, which last 5 years, in the summer of this year. The ages of the diabetic patients who will undergo tests between 18 and 60 years. Scheduled replications of the same formula, already applied, by injecting patients twice within 4 weeks. Then the patients are injected once a year during the next four years.
Questioning the results.
It should be noted that not all diabetes experts are confident that this treatment will bear fruit.
Explains Robert Sobel, Assistant Professor in Endocrinology _ Feinberg School of medicine in Endocrinology at Northwestern University, questioned the prospects for decisive results, saying: “I think it’s an exaggeration to say that this will have a major impact on millions of patients with type 1 diabetes in the world. We’d love to do something to maintain or rebuild Beta beta cell mass. Historically, we’ve seen these cells dwindle and haven’t been able to do something (in time). “
Speaking time will say about whether BCG vaccine will become a viable treatment option for type 1 diabetes or not?